阿里彩票登陆平台官网:Aquarius? film coating systems

Chemistry: Film Coating Systems

SDS Link >

阿里彩票登陆平台 www.o1e1e.com.cn Our line of fully formulated, easily dispersed and ready-to-use Aquarius™ film coating systems have a range of functions to suit almost any core. With our wide selection of film coating choices, we can provide an optimal coating for your unique formulation. The regulatory compliance information for all Ashland products varies by product family and grade. For specific data about the grade you are interested in please refer to our Excipient Information Packages and the Certificates of Analysis (COA).

Aquarius Preferred film coating systems
Aquarius Preferred film coating systems disperse easily in water. These film coatings are applicable to both pharmaceutical and nutraceutical solid dosage forms. Ashland formulators have access to an unrivaled range of cellulosic and other polymeric excipients, enabling Aquarius film coating systems to be tailored to meet exacting requirements.

To maximize the efficiency of the coating application process, high-solids loadings are desirable. By reducing the coating time using high-solids formulations, productivity is increased and overall manufacturing costs are reduced. Aquarius Preferred film coating systems are state-of-the-art immediate-release coatings, which have been scientifically formulated with careful polymer selection. High-solids cellulosic or high-solids PVP/VA formulations improve film adhesion to all substrates, especially those that offer challenges in aqueous film coating. When compared to competitive offerings, Aquarius film coating systems have proven to offer smoother, more consistent coverage even at the highest solids levels.

Clear advantages in film coating process productivity are seen with high-solids suspensions. These formulations allow the solids content of the coating system to be increased significantly (typically up to 20 percent w/w solids for pigmented coatings, and in certain cases up to 25 percent) with viscosities in the range of 100 to 300 cP.

Aquarius Prime film coating systems
Aquarius Prime film coating systems disperse easily in water and are applied to immediate-release dosage forms. Film coatings for immediate-release tablet-coating applications are typically comprised of a polymer, a plasticizer and optional pigment/opacifier. Aquarius Prime film coating systems are available in clear and white formulations off the shelf.

Aquarius Prime film coating systems can be matched to customers’ existing HPMC film coating systems. These products are useful in many applications where special coating functionality is not a major requirement. However, Ashland takes great care in formulating all film coatings in our portfolio. The selection of ingredients and ingredient levels for a formulation is a critical factor in obtaining the target appearance and performance on the tablet core and in minimizing processing problems. Optimizing a film coating formulation requires balancing critical properties, such as film strength, film adhesion, film flexibility and opacity.

Aquarius Control film coating systems
The Aquarius Control film coating systems consist of two types of coatings. Aquarius Control ENA film coating systems are delayed-release (enteric) coatings that are designed to protect active pharmaceutical ingredients (APIs) that degrade in gastric fluid, or to prevent the release of APIs that may irritate the gastric mucosa. Aquarius Control SRX film coating systems are sustained-release coatings for APIs that are most effective when released over time.

These film coating systems have predictable and controllable release retardation; are custom-formulated based on drug solubility and desired release profile; do not require a coalescence step and have stable dissolution profiles over a wide pH range. Aquarius Control film coating systems are durable, coherent coatings, in which film formation occurs via solvent evaporation – not latex coalescence – and film robustness is related to the use of a high-molecular weight polymer.

Aquarius Control SRX film coating systems are solvent-dispersible ethylcellulose (EC) coatings for multiparticulates, potentially modified with hydroxypropylcellulose (HPC) as a pore former. They are available in several different porosities that can be matched to drug solubility and/or desired release profile. A key benefit of Aquarius Control SRX film coating systems is that they do not require curing after coating.

The release profiles of tablets enteric coated with Aquarius Control ENA film coating systems are remarkably stable over periods of up to 12 months, even under accelerated stability testing.

Read More >

  • 群众工作不要听“唱功”,主要看“做功” 2018-12-09
  • 宝宝鼻子不通气怎么办 通气好方法都在这! 2018-12-09
  • 【中国梦·大国工匠篇】“景德镇拉坯第一人”占绍林:手艺“满意”前谢绝资本加入 2018-12-08
  • 【砥砺奋进的5年】空气质量优良 "南宁蓝"常驻绿城 2018-12-08
  • 俄罗斯捍卫东道主荣誉 亚洲足球何时告别“送分童子” 2018-12-08
  • 五彩丝缠角粽 民族团结一家亲 2018-12-07
  • 楼市下半年或持续降温 房地产长效机制加速推进 2018-12-07
  • 《平凡的荣耀》展现上海风情 赵又廷新剧打破职场剧套路 2018-12-07
  • 市人大常委会召开党组会议传达学习全国两会精神张轩主持并讲话 2018-12-07
  • 第11次法网封王 纳达尔红土依旧无解 2018-12-06
  • 无人值守健身房来了 会让私教下岗吗 2018-12-06
  • 沈阳日报社社长程谟刚祝贺人民日报创刊70周年 2018-12-06
  • 老夫到现在也没有明白"人民"究竟为何物。小作出来讲一讲? 2018-12-05
  • 哈佛大学被指招生歧视 亚裔生录取率大打折 2018-12-05
  • 云南女子饲养小猴子5年 竟是国家一级保护动物熊猴 2018-12-05
  • 934| 102| 454| 660| 111| 995| 356| 605| 473| 618|